Targeted Vegan Supplements: Addressing Nutrient Gaps & Boosting Brain Health

Published on 05/31/2025Trend Spotting / Early Adopter Signals

Analysis:

The discussion reveals a continued and nuanced interest in vegan nutrition and supplementation. While the original post's title suggests that certain nutrients (retinol, K2, carnitine, creatine) aren't problematic in plant-based diets, the comments provide some key insights:

  1. Established Vegan Supplement Needs: There's a general agreement that B12 and iron remain primary concerns for individuals on vegan diets, indicating a steady market for these specific supplements.
  2. Emerging Interest in Creatine for Cognitive Benefits: A significant thread is the growing awareness and discussion around creatine's positive effects on brain health and functioning. This goes beyond the traditional view of creatine solely for athletic performance. Commenters mention recent studies, suggesting this is an area of increasing consumer curiosity and potential demand.
  3. Supplementation Beyond Deficiency: Even if a vegan diet isn't "deficient" in creatine for basic needs, the idea of supplementing for enhanced cognitive function is gaining traction. This applies to both vegans and the general population.
  4. Normalizing Vegan Supplementation: There's an underlying sentiment that vegan supplementation is sometimes unfairly scrutinized, while the broader supplement market thrives.

Business & Marketing Opportunities:

Based on this, there are clear opportunities:

  1. Targeted Vegan Staples: Continue marketing high-quality, clearly-labeled vegan B12 and iron supplements. Emphasize bioavailability and sourcing.
  2. Vegan Creatine for Cognitive Health (Emerging Market):
    • Product Development: Develop and promote vegan creatine monohydrate.
    • Marketing Angle: Shift focus from purely athletic performance to cognitive benefits (memory, focus, brain health). This opens the market to students, professionals, and aging populations, including vegans who may have lower baseline creatine levels.
    • Evidence-Based Marketing: Highlight scientific studies supporting creatine's cognitive advantages. Use clear, accessible language to explain the benefits.
    • Transparency & Purity: For the vegan segment, emphasize vegan certification, purity (no animal cross-contamination), and the absence of unnecessary fillers.
  3. Bundled "Vegan Brain Health" or "Vegan Essentials" Packs: Combine B12, iron, and potentially vegan creatine (marketed for cognitive support) into convenient bundles.
  4. Educational Content Marketing: Create content (blog posts, infographics, videos) that:
    • Addresses common vegan nutritional questions.
    • Explains the science behind creatine's cognitive benefits in an easy-to-understand way.
    • Normalizes supplementation as a tool for optimizing health on any diet, including veganism.
    • Differentiates between essential nutrient supplementation (like B12 for vegans) and enhancement supplementation (like creatine for cognitive function for a broader audience).

The key is to cater to established needs (B12, iron for vegans) while capitalizing on emerging trends like creatine for cognitive function, ensuring products are high-quality, scientifically supported, and marketed with transparency, especially for the discerning vegan consumer.

Origin Reddit Post

r/science

Current evidence does not indicate that the absence of retinol, vitamin K2, carnitine, and creatine in plant-based diets adversely affect health or confer disadvantages compared to omnivorous

Posted by u/James_Fortis05/31/2025

Top Comments

u/Same_Lack_1775
Aren’t there many recent studies showing the positive effect of creatine on brain health and functioning?
u/Moonwalkers
”Endogenous synthesis adequately supports physiological needs for vitamin K2, and currently available evidence does not consistently demonstrate that dietary vitamin K2 provides additional be
u/Medical_Credit_4778
This is kind of stupid though, retinol is made from carotene k2 from natto, carnitine isnt even and issue and i don't recall creatine being necessary, b12 and iron are actual issues with vega
u/accountforrealppl
Most creatine supplements are vegan as well so if this is something that someone is worried about on a plant based diet it's quite easy to add
u/ProfessionalMockery
I expect those studies are supplementing creatine to levels beyond what you'd naturally get from meat in the diet.
u/chenzen
Preformed vitamin A(retinol being 1) is much more bioavailable than beta-carotene and peoples conversion from carotene to retinol differs a lot and can be around 12 units of carotene to 1 of
u/EsotericLion369
Well i'm alive and well, 15+ years vegan and supplement only on b12 and vitamin D. My blood works have always been fine. 
u/Same_Lack_1775
Aren’t there many recent studies showing the positive effect of creatine on brain health and functioning?
u/DavidBrooker
A narrative review is not a red flag. It's the traditional form of a literature review. For instance, the literature review chapter of most theses should be a narrative review. A systematic r
u/tectonic00
Taken from a study on the bio conversion of beta-carotene to vitamin A : "It should be remembered that human subjects may have different abilities to convert provitamin A carotenoids to vitam
u/zephyrseija2
That's definitely correct. It takes an incredible amount of red meat to get the 5g recommended daily dose of creatine.
u/ProfessionalMockery
I expect those studies are supplementing creatine to levels beyond what you'd naturally get from meat in the diet.
u/chenzen
yes [https://www.foundmyfitness.com/topics/creatine](https://www.foundmyfitness.com/topics/creatine) lots of very good studies showing benefits all over the place.
u/peppernickel
In a 6'3" redhead male that's been trying out an elimination diet since 2009. For myself, I found that I do best on a pescatarian diet that excludes wheat and dairy. Mammal products make me l
u/James_Fortis
"**Abstract** Plant-based diets are associated with numerous health benefits, including reduced risks of chronic diseases. However, questions persist regarding the implications of lower diet
u/Rurumo666
Carnitine is essential for heart health and preventing cardiomyopathy.
u/fastcatdog
The supplement market is billions a year and not because of vegans. Yet if a vegan takes one it’s all of a sudden a huge deal.
u/AnAttemptReason
If you are eating a diet high in vegetables, then you won't have issues getting enough vitamin A, even if you have the worst case conversion of beta carotene to vitamin A. Leafy greens are
u/Medical_Credit_4778
This is kind of stupid though, retinol is made from carotene k2 from natto, carnitine isnt even and issue and i don't recall creatine being necessary, b12 and iron are actual issues with vega
u/fastcatdog
The supplement market is billions a year and not because of vegans. Yet if a vegan takes one it’s all of a sudden a huge deal.
u/helm
Humans can produce creatine themselves to a varying level.
u/James_Fortis
"**Abstract** Plant-based diets are associated with numerous health benefits, including reduced risks of chronic diseases. However, questions persist regarding the implications of lower diet
u/Ballads321
“A Narrative Review” Am I missing something or is this just a hand picked bunch of studies to tell a story from their point of view?

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